Milciclib
Product Specifications
CAS Number
802539-81-7
Target
Autophagy, CDK, Trk receptor
Related Pathways
Autophagy, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint
Purity
0.9973
Bioactivity
Milciclib (PHA-848125) (PHA-848125) is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7. Phase 2.
Smiles
CNC(=O)c1nn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc-21
Molecular Formula
C25H32N8O
Molecular Weight
460.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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