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Milciclib

Product Specifications

CAS Number

802539-81-7

Target

Autophagy, CDK, Trk receptor

Related Pathways

Autophagy, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint

Purity

0.9973

Bioactivity

Milciclib (PHA-848125) (PHA-848125) is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7. Phase 2.

Smiles

CNC(=O)c1nn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc-21

Molecular Formula

C25H32N8O

Molecular Weight

460.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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