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NITD-916

Product Specifications

CAS Number

1614262-83-7

Target

Antibacterial|||Antibiotic

Related Pathways

Microbiology/Virology

Purity

0.9978

Bioactivity

NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits antituberculosis activity.

Smiles

OC1=C(C2=CC=CC=C2)C(=O)NC(CC3CCC(C)(C)CC3)=C1

Molecular Formula

C20H25NO2

Molecular Weight

311.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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