NITD-916
Product Specifications
CAS Number
1614262-83-7
Target
Antibacterial, Antibiotic
Related Pathways
Microbiology/Virology
Purity
0.9978
Bioactivity
NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits antituberculosis activity.
Smiles
OC1=C(C2=CC=CC=C2)C(=O)NC(CC3CCC(C)(C)CC3)=C1
Molecular Formula
C20H25NO2
Molecular Weight
311.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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