L82
Product Specifications
CAS Number
329227-30-7
Target
DNA, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9907
Bioactivity
L82 is a DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM) that is selective and non-competitive.L82 expresses anti-proliferative activity against breast cancer cells.
Smiles
Oc1ccc(\C=N\Nc2cn[nH]c(=O)c2Cl)cc1[N+]([O-])=O
Molecular Formula
C11H8ClN5O4
Molecular Weight
309.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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