B-Raf IN 8
Product Specifications
CAS Number
1215313-19-1
Target
Others|||Raf
Related Pathways
Others|||MAPK
Bioactivity
B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC50 = 70.65 nM) with antitumor activity, demonstrating IC50 values of 9.78, 13.78, 18.52, and 29.85 ?M against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7), and human prostate cancer (PC-3) cells [1].
Smiles
N(=CC1=CC=C(OC)C=C1)C2=CC=C(C=C2)C=3CCC(=O)NN3
Molecular Formula
C18H17N3O2
Molecular Weight
307.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/495AD9CE-241D-43B7-AA64-60378E2252C5/T60727
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1419041-06 0.02 mg (Mammalian-Cell)
Recombinant Rat Histone deacetylase 7 (Hdac7)
Ask
View Details