B-Raf IN 8
Product Specifications
CAS Number
1215313-19-1
Target
Others|||Raf
Related Pathways
Others|||MAPK
Bioactivity
B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC50 = 70.65 nM) with antitumor activity, demonstrating IC50 values of 9.78, 13.78, 18.52, and 29.85 ?M against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7), and human prostate cancer (PC-3) cells [1].
Smiles
N(=CC1=CC=C(OC)C=C1)C2=CC=C(C=C2)C=3CCC(=O)NN3
Molecular Formula
C18H17N3O2
Molecular Weight
307.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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