Aditoprime
Product Specifications
CAS Number
56066-63-8
Target
Others|||Antifolate|||Antibacterial
Related Pathways
Cell Cycle/Checkpoint|||Others|||Microbiology/Virology
Purity
0.9989
Bioactivity
Aditoprime (Aditoprim) is a selective inhibitor of bacterial dihydrofolate reductase (DHFR) that inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime shows good antibacterial activity and broad antimicrobial spectrum, and moreover, excellent pharmacokinetics. Aditoprime inhibits L.casei and E.coli DHFR with IC 50 of 520 and 47 nM, respectively [1] [2] [3].
Smiles
N(C)(C)C1=C(OC)C=C(CC=2C(N)=NC(N)=NC2)C=C1OC
Molecular Formula
C15H21N5O2
Molecular Weight
303.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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