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Aditoprime

Product Specifications

CAS Number

56066-63-8

Target

Others|||Antifolate|||Antibacterial

Related Pathways

Cell Cycle/Checkpoint|||Others|||Microbiology/Virology

Purity

0.9989

Bioactivity

Aditoprime (Aditoprim) is a selective inhibitor of bacterial dihydrofolate reductase (DHFR) that inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime shows good antibacterial activity and broad antimicrobial spectrum, and moreover, excellent pharmacokinetics. Aditoprime inhibits L.casei and E.coli DHFR with IC 50 of 520 and 47 nM, respectively [1] [2] [3].

Smiles

N(C)(C)C1=C(OC)C=C(CC=2C(N)=NC(N)=NC2)C=C1OC

Molecular Formula

C15H21N5O2

Molecular Weight

303.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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