AChE/BChE/BACE-1-IN-2
Product Specifications
CAS Number
1877000-20-8
Target
ROS Kinase, Cholinesterase (ChE), Beta-Secretase, Others
Related Pathways
Neuroscience, Tyrosine Kinase/Adaptors, Others
Bioactivity
AChE/BChE/BACE-1-IN-2 (Compound 4o) is an orally active AChE, BACE-1, and BChE inhibitor with IC50 values of 0.069, 0.097, and 0.127 μM against hAChE, hBACE-1, and hBChE, respectively. It exhibits remarkable antioxidant potential, considerable binding capability towards PAS-AChE, potential disassembly of Aβ aggregates, and neuroprotective activity against Aβ-induced stress with excellent brain permeation [1].
Smiles
C(N1CC(NCC2=C(F)C=C(F)C=C2)CC1)C3=CC=CC=C3
Molecular Formula
C18H20F2N2
Molecular Weight
302.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
032873-AP 200 µL
C1QL3, NT (C1QL3, Complement C1q-like protein 3) (AP) discontinued
Sign In for Pricing
View Details 