ZC0101
Product Specifications
CAS Number
2541604-52-6
Target
Apoptosis, Indoleamine 2,3-Dioxygenase (IDO), Reactive Oxygen Species, IDO, Others
Related Pathways
Metabolism, Immunology/Inflammation, Apoptosis, NF-κB, Others
Bioactivity
ZC0101 is a potent, orally active dual inhibitor of IDO1 (IC50 = 0.084 μM) and TrxR (IC50 = 7.98 μM), which effectively induces apoptosis and ROS accumulation in cancer cells [1].
Smiles
C(=C/C(=O)N1C(=O)C=CCC1)\C2=C(C=CC=C2)C3=CN=CN3
Molecular Formula
C17H15N3O2
Molecular Weight
293.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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