Topoisomerase I inhibitor 2
Product Specifications
CAS Number
2588211-44-1
Target
Topoisomerase, Caspase, Apoptosis, Others
Related Pathways
Proteases/Proteasome, Apoptosis, Others, DNA Damage/DNA Repair
Bioactivity
Topoisomerase I inhibitor 2 (ZML-8) is a highly selective DNA topoisomerase I (Top1) inhibitor that impedes Top1 activity, causing DNA damage. It arrests the cell cycle at the G2/M phase and induces apoptosis, exhibiting anti-tumor effects [1].
Smiles
O(C)C=1C=C2C=C3C=4C(OCC3=NC2=CC1OC)=CC=CC4
Molecular Formula
C18H15NO3
Molecular Weight
293.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880460-500 1x 500 µL
CD44 Standard (156-3C11), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470030-500 1x 500 µL
Insulin (2D11-H5), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940012-500 1x 500 µL
Tyrosinase (T311), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680181-100 1x 100 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041203-100 1x 100 µL
Smooth Muscle Actin (ACTA2/791 +1A4), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details