Topoisomerase I inhibitor 2
Selected Variant
T60617-01
Size: 25 mg
Product Specifications
CAS Number
2588211-44-1
Target
Topoisomerase, Caspase, Apoptosis, Others
Related Pathways
Proteases/Proteasome, Apoptosis, Others, DNA Damage/DNA Repair
Bioactivity
Topoisomerase I inhibitor 2 (ZML-8) is a highly selective DNA topoisomerase I (Top1) inhibitor that impedes Top1 activity, causing DNA damage. It arrests the cell cycle at the G2/M phase and induces apoptosis, exhibiting anti-tumor effects [1].
Smiles
O(C)C=1C=C2C=C3C=4C(OCC3=NC2=CC1OC)=CC=CC4
Molecular Formula
C18H15NO3
Molecular Weight
293.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Price
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