CDK1/2/4-IN-1
Product Specifications
CAS Number
2414633-49-9
Target
Others, Apoptosis, Caspase, Bcl-2 Family, CDK
Related Pathways
Others, Proteases/Proteasome, Apoptosis, Cell Cycle/Checkpoint
Bioactivity
CDK1/2/4-IN-1 (compound 3a) is a potent CDK inhibitor with IC50 values of 1.47, 0.78, and 0.87 μM for CDK1, CDK2, and CDK4, respectively. It can be used in cancer research to arrest the cell cycle at the G2/M phase and induce apoptosis, elevating Bax, caspase-3, and P53 levels while decreasing Bcl-2 levels [1].
Smiles
C(/C=C/C1=CC=C(OC)C=C1)(=O)C=2N=C(NC)SC2C
Molecular Formula
C15H16N2O2S
Molecular Weight
288.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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