Anti-inflammatory agent 11
Product Specifications
CAS Number
63932-07-0
Target
Others|||Antibacterial|||TNF
Related Pathways
Others|||Microbiology/Virology|||Apoptosis
Bioactivity
Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial agent used in tuberculosis (TB) research. It inhibits the growth of Mtb H37Rv and M299 with MIC 50 values of 1.3 and 6.9 ?M, respectively. Additionally, it reduces inflammation by suppressing iNOS expression and inhibiting NO, TNF-?, and IL-1? production [1].
Smiles
C(NNC(NCC1=CC=CC=C1)=S)(=O)C=2C=CN=CC2
Molecular Formula
C14H14N4OS
Molecular Weight
286.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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