XTT (sodium)

XTT (sodium) is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble XTT to a water-soluble, orange colored formazan product.

Product Specifications

CAS Number

[111072-31-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/xtt-sodium.html

Purity

99.85

Solubility

DMSO : 40 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

COC1=C(N2N=C(N=[N+]2C3=CC(S([O-])(=O)=O)=C(C=C3OC)[N+]([O-])=O)C(NC4=CC=CC=C4)=O)C=C(S(=O)(O[Na])=O)C([N+]([O-])=O)=C1

Molecular Formula

C22H16N7NaO13S2

Molecular Weight

673.52

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhao Q, Ernst JT, Hamilton AD, Debnath AK, Jiang S. XTT formazan widely used to detect cell viability inhibits HIV type 1 infection in vitro by targeting gp41. AIDS Res Hum Retroviruses. 2002;18 (14) :989-997. |[2]Roehm NW, et al. An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT. J Immunol Methods. 1991 Sep 13;142 (2) :257-65.