Quisinostat
Product Specifications
CAS Number
875320-29-9
Target
Apoptosis, Autophagy, HDAC
Related Pathways
Apoptosis, Chromatin/Epigenetic, DNA Damage/DNA Repair, Autophagy
Purity
0.9801
Bioactivity
Quisinostat (JNJ-26481585) (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7.
Smiles
Cn1cc(CNCC2CCN(CC2)c2ncc(cn2)C(=O)NO)c2ccccc12
Molecular Formula
C21H26N6O2
Molecular Weight
394.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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