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ARUK3001185

Product Specifications

CAS Number

2411969-39-4

Target

Wnt/beta-catenin, Others

Related Pathways

Others, Stem Cells, Cytoskeletal Signaling

Bioactivity

ARUK3001185 (Compound 8l) is a potent, selective, orally active, and brain-penetrant Notum inhibitor (IC50 = 6.7 nM), suitable for oral dosing in rodent models of disease [1].

Smiles

C(F)(F)(F)C1=C(Cl)C(=CC=C1Cl)N2C=CN=N2

Molecular Formula

C9H4Cl2F3N3

Molecular Weight

282.05

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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