SNS-032
Product Specifications
CAS Number
345627-80-7
Target
GSK-3, Apoptosis, CDK
Related Pathways
Cell Cycle/Checkpoint, Stem Cells, Apoptosis, PI3K/Akt/mTOR signaling
Purity
0.9991
Bioactivity
SNS-032 (BMS-387032) is a selective inhibitor of CDK2 (IC50: 48 nM), exhibiting 10- and 20-fold selectivity over CDK1 and CDK4, respectively. It is also sensitive to CDK7 (IC50: 62 nM) and CDK9 (IC50: 4 nM), with no effect on CDK6.
Smiles
C(SC=1SC(NC(=O)C2CCNCC2)=NC1)C=3OC(C(C)(C)C)=CN3
Molecular Formula
C17H24N4O2S2
Molecular Weight
380.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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