BTX161
Product Specifications
CAS Number
2052301-24-1
Target
Others, Casein Kinase
Related Pathways
Stem Cells, Metabolism, Others
Bioactivity
BTX161 is a Thalidomide analogue. BTX161 is a potent CKIα degrader. In human AML cells, BTX161 mediates the CKIα degradation better than Lenalidomide as well as activates DNA damage response (DDR) and p53, and also stabilizes the p53 antagonist MDM2[1].
Smiles
Cc1cccc2C(=O)N(Cc12)[C@H]1CCCC(=O)NC1=O
Molecular Formula
C15H16N2O3
Molecular Weight
272.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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