What is the catalog number for NLRP3/AIM2-IN-3?

The catalog number for NLRP3/AIM2-IN-3 is T60442.

What sizes are available for NLRP3/AIM2-IN-3?

NLRP3/AIM2-IN-3 is available in the following size(s): 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 500 mg.

How many pack sizes does NLRP3/AIM2-IN-3 come in?

NLRP3/AIM2-IN-3 is available in 7 different pack sizes.

Is NLRP3/AIM2-IN-3 in stock?

NLRP3/AIM2-IN-3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NLRP3/AIM2-IN-3?

NLRP3/AIM2-IN-3 is manufactured by Molfinity.

What is the estimated delivery time for NLRP3/AIM2-IN-3?

Estimated delivery time for NLRP3/AIM2-IN-3 is approximately 10 business day(s), depending on your location.

NLRP3/AIM2-IN-3

Product Specifications

CAS Number

1787787-60-3

Target

NOD, Pyroptosis, NOD-like Receptor (NLR), AIM2

Related Pathways

Immunology/Inflammation, NF-κB, Apoptosis

Purity

0.9716

Bioactivity

NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 is a potent inhibitor of NLRP3 and AIM2 inflammasome-dependent cell lysis with an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 inhibits LPS/nigericin NLRP3/AIM2-IN-3 inhibits LPS/nigericin-stimulated cell lysis in THP-1 macrophages with an IC50 value of 0.077 ± 0.008 μM. NLRP3/AIM2-IN-3 interferes with the interaction of NLRP3 or AIM2 with the bridging protein ASC, inhibiting oligomerization of ASC.