What is the catalog number for CAY10789?

The catalog number for CAY10789 is T60439.

What sizes are available for CAY10789?

CAY10789 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg.

How many pack sizes does CAY10789 come in?

CAY10789 is available in 4 different pack sizes.

Is CAY10789 in stock?

CAY10789 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CAY10789?

CAY10789 is manufactured by Molfinity.

What is the estimated delivery time for CAY10789?

Estimated delivery time for CAY10789 is approximately 10 business day(s), depending on your location.

CAY10789

Product Specifications

CAS Number

123226-28-8

Target

Others, Leukotriene Receptor, TNF, GPCR19

Related Pathways

Others, Apoptosis, GPCR/G Protein

Bioactivity

CAY10789 (compound 6) is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist with an IC50 of 2.80 μM and a GPBAR1 (G-protein-coupled bile acid receptor 1) agonist with an EC50 of 3 μM. It significantly decreases U937 cell adhesion to HAEC and reduces TNF-α expression. CAY10789 demonstrates promising metabolic stability and excellent pharmacokinetics, making it suitable for studying colitis, metabolic syndromes, and other GPBAR1/CysLT1R-related diseases [1].