PXS-6302
Product Specifications
CAS Number
2584947-54-4
Target
Others, Monoamine Oxidase
Related Pathways
Neuroscience, Others
Bioactivity
PXS-6302 is an irreversible inhibitor of lysyl oxidase with IC50s of 3.7 μM for Bovine LOX, 3.4 μM for rh LOXL1, 0.4 μM for rh LOXL2, 1.5 μM for rh LOXL3, 0.3 μM for rh LOXL4, respectively. PXS-6302 can readily penetrate the skin, reduces collagen deposition and cross-linking, and significantly improves scar appearance without reducing tissue strength. PXS-6302 also has potentially broader applications in other fibrotic diseases.
Smiles
S(C(/C(=C/CN)/F)(F)F)(=O)(=O)C1=CC=CC=C1
Molecular Formula
C10H10F3NO2S
Molecular Weight
265.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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