PNU-282987 free base
Product Specifications
CAS Number
711085-63-1
Target
5-HT Receptor, AChR
Related Pathways
GPCR/G Protein, Neuroscience
Purity
0.9964
Bioactivity
PNU-282987 (free base) is a potent agonist of α7 nicotinic acetylcholine receptor (nAChR) with an EC50 of 154 nM and a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. It can be used for central and peripheral nervous system studies[1].
Smiles
Clc1ccc(cc1)C(=O)N[C@H]1CN2CCC1CC2
Molecular Formula
C14H17ClN2O
Molecular Weight
264.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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