NAAA-IN-3
Product Specifications
CAS Number
1831115-59-3
Target
Others
Related Pathways
Others
Bioactivity
NAAA-IN-3 (Compound 17a) is a potent and selective NAAA inhibitor with an IC50 of 50 nM. NAAA is a cysteine amidase that preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA) . PEA is an endogenous agonist of the nuclear peroxisome proliferator-activated receptor-α (PPAR-α), a key regulator of inflammation and pain. The potential role of NAAA-IN-3 is as a therapeutic agent for the treatment of inflammation and pain.
Smiles
C(OC1CN(C#N)C1)C2=CC=C(C=C2)C3=CC=CC=C3
Molecular Formula
C17H16N2O
Molecular Weight
264.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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