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Cy5-PEG5-azide (bromide)

Cy5-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Cy5-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

UNSPSC

12171500

Target

PROTAC Linkers

Type

Dye Reagents

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cy5-peg5-azide.html

Purity

98.76

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CC(C1=CC=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(NCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)C(C=CC=C4)=C4C3(C)C.[Br-]

Molecular Formula

C44H63BrN6O6

Molecular Weight

851.91

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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