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Fenspiride

Product Specifications

CAS Number

5053-06-5

Target

Others, PDE, Histamine Receptor

Related Pathways

Immunology/Inflammation, Metabolism, GPCR/G Protein, Neuroscience, Others

Bioactivity

Fenspiride is an antagonist of H1-histamine receptors. Fenspiride is an orally active non-steroidal anti-inflammatory agent that can be used for the treatment of respiratory tract infections and otitis media. Fenspiride inhibited phosphodiesterase 4 and phosphodiesterase 3 activities with -logIC50 values of 4.16+/-0.09 and 3.44+/-0.12, respectively. Phosphodiesterase 5 activity was also inhibited with a -logIC50 value of approximately 3.8.

Smiles

O=C1OC2(CCN(CCC3=CC=CC=C3)CC2)CN1

Molecular Formula

C15H20N2O2

Molecular Weight

260.33

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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