Fenspiride
Product Specifications
CAS Number
1151767
Target
Others|||PDE|||Histamine Receptor
Related Pathways
Immunology/Inflammation|||Metabolism|||GPCR/G Protein|||Neuroscience|||Others
Bioactivity
Fenspiride is an antagonist of H1-histamine receptors. Fenspiride is an orally active non-steroidal anti-inflammatory agent that can be used for the treatment of respiratory tract infections and otitis media. Fenspiride inhibited phosphodiesterase 4 and phosphodiesterase 3 activities with -logIC50 values of 4.16+/-0.09 and 3.44+/-0.12, respectively. Phosphodiesterase 5 activity was also inhibited with a -logIC50 value of approximately 3.8.
Smiles
O=C1OC2(CCN(CCC3=CC=CC=C3)CC2)CN1
Molecular Formula
C15H20N2O2
Molecular Weight
260.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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