Tezacitabine
Product Specifications
CAS Number
130306-02-4
Target
Others, DNA/RNA Synthesis, Apoptosis, Nucleoside Antimetabolite/Analog
Related Pathways
Apoptosis, Others, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
Tezacitabine is a cytostatic and cytotoxic antimetabolite and a nucleoside analogue with a dual mechanism of action that irreversibly inhibits ribonucleotide reductase and can be incorporated into DNA during replication or repair, causing DNA chain termination. It blocks tumor cells in the G1 and S phases of the cell cycle, inducing apoptotic cell death, with potential applications in treating leukemia and solid tumors[1][2].
Smiles
Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)\C2=C/F)c(=O)n1
Molecular Formula
C10H12FN3O4
Molecular Weight
257.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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