JMS-053
Product Specifications
CAS Number
1954650-11-3
Target
Phosphatase|||Ras|||STAT
Related Pathways
JAK/STAT signaling|||Metabolism|||MAPK|||Stem Cells
Purity
?98.0%
Bioactivity
JMS-053 is a potent and selective inhibitor of the phosphatase DUSP3, inhibits PTP4A3, PTP4A1, PTP4A2 and CDC25B, inhibits cancer cell migration and sphere growth, and avoids disruption of the microvascular endothelial barrier by vascular endothelial growth factor or lipopolysaccharide.
Smiles
O=C1C2=C(SC(=C2)C3=CC=CC=C3)C(=N)C(=O)N1
Molecular Formula
C13H8N2O2S
Molecular Weight
256.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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