Nrf2-ARE/hMAO-B/QR2 modulator 1
Product Specifications
CAS Number
3035124-25-2
Target
MAO, NADPH, Reactive Oxygen Species, Monoamine Oxidase, ROS, Nrf2
Related Pathways
NF-κB, Immunology/Inflammation, Neuroscience, Metabolism
Purity
0.985
Bioactivity
Nrf2-ARE/hMAO-B/QR2 modulator 1, a resveratrol derivative and multi-target-directed ligand (mtdl), activated the NRF2-ARE pathway (CD = 9.83 μM), selectively inhibited hMAO-B and QR2 (quinone reductase-2, NQO2) (IC 50 = 8.05 and 0.57 μM), and was able to promote hippocampal neurogenesis and exert neuroprotective and antioxidant effects in an Alzheimer's disease model.
Smiles
COC1=CC=C(/C=C/C2=NN(CC#C)C(O2)=O)C=C1
Molecular Formula
C14H12N2O3
Molecular Weight
256.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6153476-01 0.1 mL
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (HRP)
Sign In for Pricing
View Details MBS6153476-02 5x 0.1 mL
MDM2 (E3 Ubiquitin-protein Ligase Mdm2, Double Minute 2 Protein, Hdm2, Oncoprotein Mdm2, p53-binding Protein Mdm2) (HRP)
Sign In for Pricing
View Details 245238-PE 100 µL
DDC (dopa Decarboxylase (aromatic L-amino Acid Decarboxylase), AADC) (PE)
Sign In for Pricing
View Details