Nrf2-ARE/hMAO-B/QR2 modulator 1
Product Specifications
CAS Number
3035124-25-2
Target
MAO, NADPH, Reactive Oxygen Species, Monoamine Oxidase, ROS, Nrf2
Related Pathways
NF-κB, Immunology/Inflammation, Neuroscience, Metabolism
Purity
0.985
Bioactivity
Nrf2-ARE/hMAO-B/QR2 modulator 1, a resveratrol derivative and multi-target-directed ligand (mtdl), activated the NRF2-ARE pathway (CD = 9.83 μM), selectively inhibited hMAO-B and QR2 (quinone reductase-2, NQO2) (IC 50 = 8.05 and 0.57 μM), and was able to promote hippocampal neurogenesis and exert neuroprotective and antioxidant effects in an Alzheimer's disease model.
Smiles
COC1=CC=C(/C=C/C2=NN(CC#C)C(O2)=O)C=C1
Molecular Formula
C14H12N2O3
Molecular Weight
256.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6181686-01 0.1 mL
TNFRSF19 (Tumor Necrosis Factor Receptor Superfamily, Member 19, TAJ, TAJ-alpha, TRADE, TROY) (HRP)
Sign In for Pricing
View Details MBS6181686-02 5x 0.1 mL
TNFRSF19 (Tumor Necrosis Factor Receptor Superfamily, Member 19, TAJ, TAJ-alpha, TRADE, TROY) (HRP)
Sign In for Pricing
View Details 53060141 1x 10^6 Cells / 1.0 mL
ASSP4 CRISPR Knock Out 293T Cell Line (Human)
Sign In for Pricing
View Details 