Brivanib
Product Specifications
CAS Number
649735-46-6
Target
Autophagy, EGFR, FGFR, VEGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Autophagy, Angiogenesis
Purity
0.9887
Bioactivity
Brivanib (BMS-540215) is an ATP-competitive inhibitor targeting VEGFR2 with an IC50 of 25 nM, exhibiting moderate potency against VEGFR-1 and FGFR-1, and over 240-fold selectivity against PDGFR-β. Phase 3.
Smiles
C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C
Molecular Formula
C19H19FN4O3
Molecular Weight
370.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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