Brivanib

Product Specifications

CAS Number

649735-46-6

Target

Autophagy|||EGFR|||FGFR|||VEGFR

Related Pathways

Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Autophagy|||Angiogenesis

Purity

0.9887

Bioactivity

Brivanib (BMS-540215) is an ATP-competitive inhibitor targeting VEGFR2 with an IC50 of 25 nM, exhibiting moderate potency against VEGFR-1 and FGFR-1, and over 240-fold selectivity against PDGFR-?. Phase 3.

Smiles

C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C

Molecular Formula

C19H19FN4O3

Molecular Weight

370.38

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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