LY367385 hydrochloride
Product Specifications
CAS Number
2829282-00-8
Target
Others|||GluR
Related Pathways
Neuroscience|||Others
Bioactivity
LY367385 hydrochloride is a potent and selective mGluR1a antagonist with an IC50 value of 8.8 ?M for inhibiting quisqualate-induced phosphoinositide (PI) hydrolysis, showing significantly higher selectivity compared to its >100 ?M IC50 value for mGlu5a. This compound exhibits neuroprotective, anticonvulsant, and antiepileptic effects [1] [2].
Smiles
[C@H](C(O)=O)(N)C1=C(C)C=C(C(O)=O)C=C1.Cl
Molecular Formula
C10H12ClNO4
Molecular Weight
245.66
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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