KDM4-IN-4
Product Specifications
CAS Number
2230475-63-3
Target
Histone Demethylase
Related Pathways
Chromatin/Epigenetic
Purity
0.9961
Bioactivity
KDM4-IN-4 (compound 47) is a potent inhibitor of histone lysine demethylase 4 (KDM4), with a binding constant of approximately 80 μM for the KDM4A-Tudor domain. It inhibits H3K4Me3 binding to the Tudor domain in cellular contexts with an EC50 value of 105 μM, holding potential for anticancer research applications [1].
Smiles
O[C@@H]1[C@]2(C[C@@]([C@@H]1CN(C)C)(CC2)[H])C3=CC=CC=C3
Molecular Formula
C16H23NO
Molecular Weight
245.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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