Pyruvate Carboxylase-IN-1
Product Specifications
CAS Number
70205-50-4
Target
Others, Mitochondrial Metabolism
Related Pathways
Metabolism, Others
Bioactivity
Pyruvate Carboxylase-IN-1 (compound 37), a natural analog of erianin, is a potent inhibitor of pyruvate carboxylase (PC), with inhibitory concentrations (IC50) of 0.204 μM and 0.104 μM in cell lysate-based and cell-based PC activity assays, respectively. This compound effectively inhibits PC enzymatic activity, contributing to its anticancer effects in human hepatocellular carcinoma (HCC) [1].
Smiles
OC1=C2C=3C(CCC2=CC(OC)=C1)=CC=CC3O
Molecular Formula
C15H14O3
Molecular Weight
242.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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