ROS 234
Product Specifications
CAS Number
184576-87-2
Target
Others, Histamine Receptor
Related Pathways
Others, Immunology/Inflammation, Neuroscience, GPCR/G Protein
Bioactivity
ROS 234 is a highly effective H3 antagonist, demonstrating a strong binding affinity (pK B) of 9.46 for the Guinea-pig ileum H3 receptor and a pKi of 8.90 for the Rat cerebral cortex H3 receptor. Additionally, it exhibits an ex vivo ED50 of 19.12 mg/kg (ip) in the Rat cerebral cortex. It should be noted that ROS 234 demonstrates limited central access, as reported in [1] and [2].
Smiles
N(CCCC1=CN=CN1)C=2NC=3C(N2)=CC=CC3
Molecular Formula
C13H15N5
Molecular Weight
241.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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