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UMI-77

Product Specifications

CAS Number

518303-20-3

Target

Bcl-2 Family

Related Pathways

Apoptosis

Purity

0.9957

Bioactivity

UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1 with a Ki of 490 nM and is selective over other members of the Bcl-2 family.

Smiles

OC(=O)CSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O

Molecular Formula

C18H14BrNO5S2

Molecular Weight

468.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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