UMI-77
Product Specifications
CAS Number
518303-20-3
Target
Bcl-2 Family
Related Pathways
Apoptosis
Purity
0.9957
Bioactivity
UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1 with a Ki of 490 nM and is selective over other members of the Bcl-2 family.
Smiles
OC(=O)CSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O
Molecular Formula
C18H14BrNO5S2
Molecular Weight
468.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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MBS616148-01 0.1 mL
Oct4 (POU Domain, Class 5, Transcription Factor 1 Oct3/4, POU5F1, HGNC:9221, MGC22487, Octamer-binding Transcription Factor 3, Oct3, OTF3, OTF4, POU-type Homeodomain-containing DNA-binding Protein)
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MBS616148-02 5x 0.1 mL
Oct4 (POU Domain, Class 5, Transcription Factor 1 Oct3/4, POU5F1, HGNC:9221, MGC22487, Octamer-binding Transcription Factor 3, Oct3, OTF3, OTF4, POU-type Homeodomain-containing DNA-binding Protein)
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