XL388
Product Specifications
CAS Number
1251156-08-7
Target
PI3K|||mTOR|||Autophagy|||Cytochromes P450
Related Pathways
Metabolism|||Autophagy|||PI3K/Akt/mTOR signaling
Purity
0.9953
Bioactivity
XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR (IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.
Smiles
Cc1c(F)c(ccc1C(=O)N1CCOc2ccc(cc2C1)-c1ccc(N)nc1)S(C)(=O)=O
Molecular Formula
C23H22FN3O4S
Molecular Weight
455.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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