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XL388

Product Specifications

CAS Number

1251156-08-7

Target

PI3K|||mTOR|||Autophagy|||Cytochromes P450

Related Pathways

Metabolism|||Autophagy|||PI3K/Akt/mTOR signaling

Purity

0.9953

Bioactivity

XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR (IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.

Smiles

Cc1c(F)c(ccc1C(=O)N1CCOc2ccc(cc2C1)-c1ccc(N)nc1)S(C)(=O)=O

Molecular Formula

C23H22FN3O4S

Molecular Weight

455.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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