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PF 477736

Product Specifications

CAS Number

952021-60-2

Target

VEGFR, c-RET, Chk, FGFR, FLT, Aurora Kinase, c-Fms, CDK, Src

Related Pathways

Cell Cycle/Checkpoint, Apoptosis, Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9994

Bioactivity

PF 477736 (PF-736, PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.

Smiles

Cn1cc(cn1)-c1[nH]c2cc(NC(=O)[C@H](N)C3CCCCC3)cc3c2c1cn[nH]c3=O

Molecular Formula

C22H25N7O2

Molecular Weight

419.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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