PF 477736
Product Specifications
CAS Number
952021-60-2
Target
VEGFR, c-RET, Chk, FGFR, FLT, Aurora Kinase, c-Fms, CDK, Src
Related Pathways
Cell Cycle/Checkpoint, Apoptosis, Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9994
Bioactivity
PF 477736 (PF-736, PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
Smiles
Cn1cc(cn1)-c1[nH]c2cc(NC(=O)[C@H](N)C3CCCCC3)cc3c2c1cn[nH]c3=O
Molecular Formula
C22H25N7O2
Molecular Weight
419.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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