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Mirin

Product Specifications

CAS Number

299953-00-7

Target

ATM/ATR

Related Pathways

DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

Purity

0.9924

Bioactivity

Mirin is a Mre11-Rad50-Nbs1 (MRN) complex inhibitor that inhibits MRN-dependent ATM activation without affecting ATM protein kinase activity. It also inhibits Mre11-associated exonuclease activity, thereby disrupting DNA double-strand break repair.Mirin induces cell cycle arrest in G1 phase.

Smiles

O=C1N=C(SC1=CC2=CC=C(O)C=C2)N

Molecular Formula

C10H8N2O2S

Molecular Weight

220.25

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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