Mirin
Product Specifications
CAS Number
299953-00-7
Target
ATM/ATR
Related Pathways
DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Purity
0.9924
Bioactivity
Mirin is a Mre11-Rad50-Nbs1 (MRN) complex inhibitor that inhibits MRN-dependent ATM activation without affecting ATM protein kinase activity. It also inhibits Mre11-associated exonuclease activity, thereby disrupting DNA double-strand break repair.Mirin induces cell cycle arrest in G1 phase.
Smiles
O=C1N=C(SC1=CC2=CC=C(O)C=C2)N
Molecular Formula
C10H8N2O2S
Molecular Weight
220.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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