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SIRT-IN-3

Product Specifications

CAS Number

1211-19-4

Target

Others, Sirtuin

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic, Others

Bioactivity

SIRT-IN-3, a potent inhibitor of SIRT1 with an IC50 value of 17 μM, exhibits approximate 4-fold and 14-fold greater selectivity for SIRT1 over SIRT2 and SIRT3, with respective IC50 values of 74 μM for SIRT2 and 235 μM for SIRT3 [1].

Smiles

NC(=O)c1ccccc1Nc1ccccc1

Molecular Formula

C13H12N2O

Molecular Weight

212.25

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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