SIRT-IN-3
Product Specifications
CAS Number
1211-19-4
Target
Others|||Sirtuin
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Others
Bioactivity
SIRT-IN-3, a potent inhibitor of SIRT1 with an IC50 value of 17 ?M, exhibits approximate 4-fold and 14-fold greater selectivity for SIRT1 over SIRT2 and SIRT3, with respective IC50 values of 74 ?M for SIRT2 and 235 ?M for SIRT3 [1].
Smiles
NC(=O)c1ccccc1Nc1ccccc1
Molecular Formula
C13H12N2O
Molecular Weight
212.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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