Pacritinib
Product Specifications
CAS Number
937272-79-2
Target
JAK, FLT, Tyrosine Kinases
Related Pathways
Stem Cells, JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic
Purity
0.9952
Bioactivity
Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays) .
Smiles
C(CN1CCCC1)Oc1ccc2Nc3nccc(n3)-c3cccc(COC\C=C\COCc1c2)c3
Molecular Formula
C28H32N4O3
Molecular Weight
472.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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