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Volasertib

Product Specifications

Target

Apoptosis|||PLK

Related Pathways

Apoptosis|||Cell Cycle/Checkpoint

Purity

0.9972

Bioactivity

Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis. It also inhibits PLK2/PLK3 (IC50s: 5/56 nM) .

Smiles

CC[C@H]1N(C(C)C)c2nc(Nc3ccc(cc3OC)C(=O)N[C@H]3CC[C@@H](CC3)N3CCN(CC4CC4)CC3)ncc2N(C)C1=O

Molecular Formula

C34H50N8O3

Molecular Weight

618.81

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/BF2C6004-E8BE-4DF9-B175-9C19157861CE/T6019

CAS Number

755038-65-4

Available Sizes

Curated Selection

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